Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. [1]

Titolo	Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Publication Type	Journal Article
Authors	Ligthart, S [2], Vaez, A [3], Võsa, U [4], Stathopoulou, MG [5], de Vries, PS [6], Prins, BP [7], van der Most, PJ [8], Tanaka, T [9], Naderi, E [10], Rose, LM [11], Wu, Y [12], Karlsson, R [13], Barbalic, M [14], Lin, H [15], Pool, R [16], Zhu, G [17], Macé, A [18], Sidore, C [19], Trompet, S [20], Mangino, M [21], Sabater-Lleal, M [22], Kemp, JP [23], Abbasi, A [24], Kacprowski, T [25], Verweij, N [26], Smith, AV [27], Huang, T [28], Marzi, C [29], Feitosa, MF [30], Lohman, KK [31], Kleber, ME [32], Milaneschi, Y [33], Mueller, C [34], Huq, M [35], Vlachopoulou, E [36], Lyytikäinen, L-P [37], Oldmeadow, C [38], Deelen, J [39], Perola, M [40], Zhao, JHua [41], Feenstra, B [42], Amini, M [43], Lahti, J [44], Schraut, KE [45], Fornage, M [46], Suktitipat, B [47], Chen, W-M [48], Li, X [49], Nutile, T [50], Malerba, G [51], Luan, J'an [52], Bak, T [53], Schork, N [54], M, Fdel Greco [55], Thiering, E [56], Mahajan, A [57], Marioni, RE [58], Mihailov, E [59], Eriksson, J [60], Ozel, ABilge [61], Zhang, W [62], Nethander, M [63], Cheng, Y-C [64], Aslibekyan, S [65], Ang, W [66], Gandin, I [67], Yengo, L [68], Portas, L [69], Kooperberg, C [70], Hofer, E [71], Rajan, KB [72], Schurmann, C [73], Hollander, Wden [74], Ahluwalia, TS [75], Zhao, J [76], Draisma, HHM [77], Ford, I [78], Timpson, N [79], Teumer, A [80], Huang, H [81], Wahl, S [82], Liu, Y [83], Huang, J [84], Uh, H-W [85], Geller, F [86], Joshi, PK [87], Yanek, LR [88], Trabetti, E [89], Lehne, B [90], Vozzi, D [91], Verbanck, M [92], Biino, G [93], Saba, Y [94], Meulenbelt, I [95], O'Connell, JR [96], Laakso, M [97], Giulianini, F [98], Magnusson, PKE [99], Ballantyne, CM [100], Hottenga, JJan [101], Montgomery, GW [102], Rivadineira, F [103], Rueedi, R [104], Steri, M [105], Herzig, K-H [106], Stott, DJ [107], Menni, C [108], Frånberg, M [109], St Pourcain, B [110], Felix, SB [111], Pers, TH [112], Bakker, SJL [113], Kraft, P [114], Peters, A [115], Vaidya, D [116], Delgado, G [117], Smit, JH [118], Großmann, V [119], Sinisalo, J [120], Seppälä, I [121], Williams, SR [122], Holliday, EG [123], Moed, M [124], Langenberg, C [125], Räikkönen, K [126], Ding, J [127], Campbell, H [128], Sale, MM [129], Chen, Y-DI [130], James, AL [131], Ruggiero, D [132], Soranzo, N [133], Hartman, CA [134], Smith, EN [135], Berenson, GS [136], Fuchsberger, C [137], Hernandez, D [138], Tiesler, CMT [139], Giedraitis, V [140], Liewald, D [141], Fischer, K [142], Mellström, D [143], Larsson, A [144], Wang, Y [145], Scott, WR [146], Lorentzon, M [147], Beilby, J [148], Ryan, KA [149], Pennell, CE [150], Vuckovic, D [151], Balkau, B [152], Concas, MPina [153], Schmidt, R [154], de Leon, CFMendes [155], Bottinger, EP [156], Kloppenburg, M [157], Paternoster, L [158], Boehnke, M [159], Musk, AW [160], Willemsen, G [161], Evans, DM [162], Madden, PAF [163], Kähönen, M [164], Kutalik, Z [165], Zoledziewska, M [166], Karhunen, V [167], Kritchevsky, SB [168], Sattar, N [169], LaChance, G [170], Clarke, R [171], Harris, TB [172], Raitakari, OT [173], Attia, JR [174], van Heemst, D [175], Kajantie, E [176], Sorice, R [177], Gambaro, G [178], Scott, RA [179], Hicks, AA [180], Ferrucci, L [181], Standl, M [182], Lindgren, CM [183], Starr, JM [184], Karlsson, M [185], Lind, L [186], Li, JZ [187], Chambers, JC [188], Mori, TA [189], de Geus, EJCN [190], Heath, AC [191], Martin, NG [192], Auvinen, J [193], Buckley, BM [194], de Craen, AJM [195], Waldenberger, M [196], Strauch, K [197], Meitinger, T [198], Scott, RJ [199], McEvoy, M [200], Beekman, M [201], Bombieri, C [202], Ridker, PM [203], Mohlke, KL [204], Pedersen, NL [205], Morrison, AC [206], Boomsma, DI [207], Whitfield, JB [208], Strachan, DP [209], Hofman, A [210], Vollenweider, P [211], Cucca, F [212], Järvelin, M-R [213], J Jukema, W [214], Spector, TD [215], Hamsten, A [216], Zeller, T [217], Uitterlinden, AG [218], Nauck, M [219], Gudnason, V [220], Qi, L [221], Grallert, H [222], Borecki, IB [223], Rotter, JI [224], März, W [225], Wild, PS [226], Lokki, M-L [227], Boyle, M [228], Salomaa, V [229], Melbye, M [230], Eriksson, JG [231], Wilson, JF [232], Penninx, BWJH [233], Becker, DM [234], Worrall, BB [235], Gibson, G [236], Krauss, RM [237], Ciullo, M [238], Zaza, G [239], Wareham, NJ [240], Oldehinkel, AJ [241], Palmer, LJ [242], Murray, SS [243], Pramstaller, PP [244], Bandinelli, S [245], Heinrich, J [246], Ingelsson, E [247], Deary, IJ [248], Mägi, R [249], Vandenput, L [250], van der Harst, P [251], Desch, KC [252], Kooner, JS [253], Ohlsson, C [254], Hayward, C [255], Lehtimäki, T [256], Shuldiner, AR [257], Arnett, DK [258], Beilin, LJ [259], Robino, A [260], Froguel, P [261], Pirastu, M [262], Jess, T [263], Koenig, W [264], Loos, RJF [265], Evans, DA [266], Schmidt, H [267], Smith, GDavey [268], P Slagboom, E [269], Eiriksdottir, G [270], Morris, AP [271], Psaty, BM [272], Tracy, RP [273], Nolte, IM [274], Boerwinkle, E [275], Visvikis-Siest, S [276], Reiner, AP [277], Gross, M [278], Bis, JC [279], Franke, L [280], Franco, OH [281], Benjamin, EJ [282], Chasman, DI [283], Dupuis, J [284], Snieder, H [285], Dehghan, A [286], Alizadeh, BZ [287]
Corporate Authors	LifeLines Cohort Study, [288], CHARGE Inflammation Working Group [289]
PubMed ID	30388399 [290]
PubMed Central ID	PMC6218410
Grant List	U01 HL130114 / HL / NHLBI NIH HHS / United States MR/J012165/1 / / Medical Research Council / United Kingdom MR/K026992/1 / / Medical Research Council / United Kingdom MC_UU_12015/1 / / Medical Research Council / United Kingdom MC_UU_12013/4 / / Medical Research Council / United Kingdom G0700704 / / Medical Research Council / United Kingdom R01 HL141399 / HL / NHLBI NIH HHS / United States