Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. [1]

Titolo	Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Publication Type	Journal Article
Authors	Day, FR [2], Ruth, KS [3], Thompson, DJ [4], Lunetta, KL [5], Pervjakova, N [6], Chasman, DI [7], Stolk, L [8], Finucane, HK [9], Sulem, P [10], Bulik-Sullivan, B [11], Esko, T [12], Johnson, AD [13], Elks, CE [14], Franceschini, N [15], He, C [16], Altmaier, E [17], Brody, JA [18], Franke, LL [19], Huffman, JE [20], Keller, MF [21], McArdle, PF [22], Nutile, T [23], Porcu, E [24], Robino, A [25], Rose, LM [26], Schick, UM [27], Smith, JA [28], Teumer, A [29], Traglia, M [30], Vuckovic, D [31], Yao, J [32], Zhao, W [33], Albrecht, E [34], Amin, N [35], Corre, T [36], Hottenga, J-J [37], Mangino, M [38], Smith, AV [39], Tanaka, T [40], Abecasis, GR [41], Andrulis, IL [42], Anton-Culver, H [43], Antoniou, AC [44], Arndt, V [45], Arnold, AM [46], Barbieri, C [47], Beckmann, MW [48], Beeghly-Fadiel, A [49], Benitez, J [50], Bernstein, L [51], Bielinski, SJ [52], Blomqvist, C [53], Boerwinkle, E [54], Bogdanova, NV [55], Bojesen, SE [56], Bolla, MK [57], Borresen-Dale, A-L [58], Boutin, TS [59], Brauch, H [60], Brenner, H [61], Brüning, T [62], Burwinkel, B [63], Campbell, A [64], Campbell, H [65], Chanock, SJ [66], J Chapman, R [67], Chen, Y-DIda [68], Chenevix-Trench, G [69], Couch, FJ [70], Coviello, AD [71], Cox, A [72], Czene, K [73], Darabi, H [74], De Vivo, I [75], Demerath, EW [76], Dennis, J [77], Devilee, P [78], Dörk, T [79], Dos-Santos-Silva, I [80], Dunning, AM [81], Eicher, JD [82], Fasching, PA [83], Faul, JD [84], Figueroa, J [85], Flesch-Janys, D [86], Gandin, I [87], Garcia, ME [88], García-Closas, M [89], Giles, GG [90], Girotto, GG [91], Goldberg, MS [92], González-Neira, A [93], Goodarzi, MO [94], Grove, ML [95], Gudbjartsson, DF [96], Guenel, P [97], Guo, X [98], Haiman, CA [99], Hall, P [100], Hamann, U [101], Henderson, BE [102], Hocking, LJ [103], Hofman, A [104], Homuth, G [105], Hooning, MJ [106], Hopper, JL [107], Hu, FB [108], Huang, J [109], Humphreys, K [110], Hunter, DJ [111], Jakubowska, A [112], Jones, SE [113], Kabisch, M [114], Karasik, D [115], Knight, JA [116], Kolcic, I [117], Kooperberg, C [118], Kosma, V-M [119], Kriebel, J [120], Kristensen, V [121], Lambrechts, D [122], Langenberg, C [123], Li, J [124], Li, X [125], Lindström, S [126], Liu, Y [127], Luan, J'an [128], Lubinski, J [129], Mägi, R [130], Mannermaa, A [131], Manz, J [132], Margolin, S [133], Marten, J [134], Martin, NG [135], Masciullo, C [136], Meindl, A [137], Michailidou, K [138], Mihailov, E [139], Milani, L [140], Milne, RL [141], Müller-Nurasyid, M [142], Nalls, M [143], Neale, BM [144], Nevanlinna, H [145], Neven, P [146], Newman, AB [147], Nordestgaard, BG [148], Olson, JE [149], Padmanabhan, S [150], Peterlongo, P [151], Peters, U [152], Petersmann, A [153], Peto, J [154], Pharoah, PDP [155], Pirastu, NN [156], Pirie, A [157], Pistis, G [158], Polasek, O [159], Porteous, D [160], Psaty, BM [161], Pylkäs, K [162], Radice, P [163], Raffel, LJ [164], Rivadeneira, F [165], Rudan, I [166], Rudolph, A [167], Ruggiero, D [168], Sala, CF [169], Sanna, S [170], Sawyer, EJ [171], Schlessinger, D [172], Schmidt, MK [173], Schmidt, F [174], Schmutzler, RK [175], Schoemaker, MJ [176], Scott, RA [177], Seynaeve, CM [178], Simard, J [179], Sorice, R [180], Southey, MC [181], Stöckl, D [182], Strauch, K [183], Swerdlow, A [184], Taylor, KD [185], Thorsteinsdottir, U [186], Toland, AE [187], Tomlinson, I [188], Truong, T [189], Tryggvadottir, L [190], Turner, ST [191], Vozzi, D [192], Wang, Q [193], Wellons, M [194], Willemsen, G [195], Wilson, JF [196], Winqvist, R [197], Wolffenbuttel, BBHR [198], Wright, AF [199], Yannoukakos, D [200], Zemunik, T [201], Zheng, W [202], Zygmunt, M [203], Bergmann, S [204], Boomsma, DI [205], Buring, JE [206], Ferrucci, L [207], Montgomery, GW [208], Gudnason, V [209], Spector, TD [210], van Duijn, CM [211], Alizadeh, BZ [212], Ciullo, M [213], Crisponi, L [214], Easton, DF [215], Gasparini, PP [216], Gieger, C [217], Harris, TB [218], Hayward, C [219], Kardia, SLR [220], Kraft, P [221], McKnight, B [222], Metspalu, A [223], Morrison, AC [224], Reiner, AP [225], Ridker, PM [226], Rotter, JI [227], Toniolo, D [228], Uitterlinden, AG [229], Ulivi, S [230], Völzke, H [231], Wareham, NJ [232], Weir, DR [233], Yerges-Armstrong, LM [234], Price, AL [235], Stefansson, K [236], Visser, JA [237], Ong, KK [238], Chang-Claude, J [239], Murabito, JM [240], Perry, JRB [241], Murray, A [242]
Corporate Authors	PRACTICAL Consortium [243], kConFab investigators [244], AOCS Investigators [245], Generation Scotland [246], EPIC-InterAct Consortium [247], LifeLines Cohort Study, [248]
PubMed ID	26414677 [249]
PubMed Central ID	PMC4661791
Grant List	MC_UU_12015/2 / / Medical Research Council / United Kingdom