@article {10545, title = {Higher growth, fat and fat-free masses correlate with larger cerebellar volumes in preterm infants at term.}, journal = {Acta Paediatr}, volume = {106}, year = {2017}, month = {2017 Jun}, pages = {918-925}, abstract = {

AIM: Smaller cerebellar volumes in very low-birthweight (VLBW) infants at term have been related to adverse cognitive outcomes, and this study evaluated whether these volumes were associated with a growth in body composition during hospital stays.

METHODS: We prospectively recruited 42 VLBW infants from an Italian neonatal unit between January 2013 and August 2015. Cerebellar volumes and body composition were measured by magnetic resonance imaging (MRI) and air-displacement plethysmography, respectively, at 40 weeks of gestational age and anthropometric and nutritional data were collected. We also included 20 term-born controls.

RESULTS: The mean gestational age and birthweight of the VLBW infants were 29.4 ({\textpm}1.9) weeks and 1120 ({\textpm}290) g. There was a positive correlation between cerebellar volumes and daily weight gain from birth to term (R = 0.26, p = 0.001), weight (R = 0.25, p = 0.001), length (R = 0.16, p = 0.01), fat mass (R = 0.15, p = 0.01) and fat-free mass at term (R = 0.20, p = 0.003). In multiple regression analysis, daily weight gain, mechanical ventilation and postconceptional age at MRI were independently associated with cerebellar volumes. Anthropometric data and cerebellar volumes were similar between VLBW and control infants.

CONCLUSION: Higher growth, higher fat mass and fat-free mass were associated with larger cerebellar volumes in VLBW infants at term.

}, keywords = {Body Composition, Cerebellum, Child Development, Female, Humans, Infant, Newborn, Infant, Premature, Infant, Very Low Birth Weight, Male, Nutritional Status, Organ Size, Prospective Studies, Regression Analysis}, issn = {1651-2227}, doi = {10.1111/apa.13829}, author = {Paviotti, Giulia and De Cunto, Angela and Zennaro, Floriana and Boz, Giulia and Travan, Laura and Cont, Gabriele and Bua, Jenny and Demarini, Sergio} } @article {3534, title = {High-frequency percussive ventilation as rescue treatment in severe hypoxemic respiratory failure in term neonates.}, journal = {J Crit Care}, volume = {29}, year = {2014}, month = {2014 Aug}, pages = {662-3}, keywords = {Female, High-Frequency Ventilation, Humans, Male, Oxygen, Pulmonary Gas Exchange, Respiratory Insufficiency}, issn = {1557-8615}, doi = {10.1016/j.jcrc.2014.02.018}, author = {Paviotti, Giulia and Bua, Jenny and De Cunto, Angela and Travan, Laura and Demarini, Sergio} } @article {1860, title = {Human colostrum and breast milk contain high levels of TNF-related apoptosis-inducing ligand (TRAIL).}, journal = {J Hum Lact}, volume = {29}, year = {2013}, month = {2013 Feb}, pages = {23-5}, abstract = {

BACKGROUND: TNF-related apoptosis inducing ligand (TRAIL) is a pleiotropic cytokine, which plays a key role in the immune system as well as in controlling the balance of apoptosis and proliferation in various organs and tissues.

OBJECTIVE: To investigate the presence and levels of soluble TRAIL in human colostrum and milk.

METHODS: The levels of soluble human TRAIL were measured in human colostrum (day 2 after delivery) and breast milk (day 5 after delivery). The presence of TRAIL was also measured in infant formula.

RESULTS: Levels of soluble TRAIL in the colostrum and mature human milk were, respectively, at least 400 and 100 fold higher than those detected in human serum. No TRAIL was detected in formula.

CONCLUSION: Human soluble TRAIL is present at extremely high levels in human colostrum and human milk and might have a significant role in mediating the anti-cancer activity of human milk.

}, keywords = {Adult, Apgar Score, Colostrum, Female, Gestational Age, Humans, Infant Formula, Infant, Newborn, Milk, Human, TNF-Related Apoptosis-Inducing Ligand}, issn = {1552-5732}, doi = {10.1177/0890334412441071}, author = {Davanzo, Riccardo and Zauli, Giorgio and Monasta, Lorenzo and Vecchi Brumatti, Liza and Abate, Maria Valentina and Ventura, Giovanna and Rimondi, Erika and Secchiero, Paola and Demarini, Sergio} } @article {1648, title = {Hot water and preparation of infant formula: how hot does it have to be to be safe?}, journal = {J Pediatr Gastroenterol Nutr}, volume = {50}, year = {2010}, month = {2010 Mar}, pages = {352-3}, keywords = {Guidelines as Topic, Hot Temperature, Humans, Infant, Infant Formula, Water, World Health Organization}, issn = {1536-4801}, doi = {10.1097/MPG.0b013e31819f65b1}, author = {Davanzo, Riccardo and Giurici, Nagua and Demarini, Sergio} }