@article {3627,
	title = {Curcumin and inflammatory bowel disease: potential and limits of innovative treatments.},
	journal = {Molecules},
	volume = {19},
	year = {2014},
	month = {2014},
	pages = {21127-53},
	abstract = {<p>Curcumin belongs to the family of natural compounds collectively called curcuminoids and it possesses remarkable beneficial anti-oxidant, anti-inflammatory, anti-cancer, and neuroprotective properties. Moreover it is commonly assumed that curcumin has also been suggested as a remedy for digestive diseases such as inflammatory bowel diseases (IBD), a chronic immune disorder affecting the gastrointestinal tract and that can be divided in two major subgroups: Crohn{\textquoteright}s disease (CD) and Ulcerative Colitis (UC), depending mainly on the intestine tract affected by the inflammatory events. The chronic and intermittent nature of IBD imposes, where applicable, long-term treatments conducted in most of the cases combining different types of drugs. In more severe cases and where there has been no good response to the drugs, a surgery therapy is carried out. Currently, IBD-pharmacological treatments are generally not curative and often present serious side effects; for this reason, being known the relationship between nutrition and IBD, it is worthy of interesting the study and the development of new dietary strategy. The curcumin principal mechanism is the suppression of IBD inflammatory compounds (NF-κB) modulating immune response. This review summarizes literature data of curcumin as anti-inflammatory and anti-oxidant in IBD, trying to understand the different effects in CD e UC.</p>},
	keywords = {Animals, Anti-Inflammatory Agents, Non-Steroidal, Chemistry, Pharmaceutical, Clinical Trials as Topic, Curcumin, Humans, Inflammatory Bowel Diseases, Molecular Targeted Therapy, Nanotechnology, Treatment Outcome},
	issn = {1420-3049},
	doi = {10.3390/molecules191221127},
	author = {Vecchi Brumatti, Liza and Marcuzzi, Annalisa and Tricarico, Paola Maura and Zanin, Valentina and Girardelli, Martina and Bianco, Anna Monica}
}
@article {1904,
	title = {Clarification of the pleiotropic effects of statins on mevalonate pathway and the feedback regulation of isoprenoids requires more comprehensive investigation.},
	journal = {Cell Biochem Funct},
	volume = {30},
	year = {2012},
	month = {2012 Mar},
	pages = {176},
	keywords = {Carcinoma, Hepatocellular, Enzyme Inhibitors, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Liver Neoplasms, Simvastatin, Terpenes},
	issn = {1099-0844},
	doi = {10.1002/cbf.2798},
	author = {Bianco, Anna Monica and Zanin, Valentina and Marcuzzi, Annalisa and Crovella, Sergio}
}
@article {1842,
	title = {Comments to the editor concerning the paper entitled "Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways" Shiekh Tanveer Ahmad et al.},
	journal = {Toxicology},
	volume = {293},
	year = {2012},
	month = {2012 Mar 11},
	pages = {123-4},
	keywords = {Animals, Antineoplastic Agents, Kidney Neoplasms, Male, Signal Transduction, Terpenes},
	issn = {1879-3185},
	doi = {10.1016/j.tox.2011.12.008},
	author = {Vuch, Josef and Marcuzzi, Annalisa and Zanin, Valentina and Crovella, Sergio}
}
@article {1864,
	title = {A common genetic background could explain early-onset Crohn{\textquoteright}s disease.},
	journal = {Med Hypotheses},
	volume = {78},
	year = {2012},
	month = {2012 Apr},
	pages = {520-2},
	abstract = {<p>Crohn{\textquoteright}s disease (CD) is a multifactorial disease, in which environmental, microbial and genetic factors play important roles. CD is characterized by a chronic granulomatous inflammation by necrotic scarring with aspects of full-thickness wall. In spite of affecting mainly young adults, sometimes, CD can be present in the first year of life (early onset Crohn disease, EOCD) showing an unpredictable course and being often more severe than at older ages. In this paper we propose the hypothesis that EOCD patients should be analyzed using a Mendelian approach with family studies aimed to identify new loci directly involved in the early onset Crohn{\textquoteright}s disease. So we will leave the classic association study approach used until now for the identification of genes responsible for susceptibility to CD and propose linkage family analysis as alternative and powerful tool for the identification of new genetic variants associated with familiar cases of EOCD.</p>},
	keywords = {Crohn Disease, Genetic Linkage, Genetic Predisposition to Disease, Humans, Models, Biological},
	issn = {1532-2777},
	doi = {10.1016/j.mehy.2012.01.023},
	author = {Bianco, Anna Monica and Zanin, Valentina and Girardelli, Martina and Magnolato, Andrea and Martelossi, Stefano and Martellossi, Stefano and Tommasini, Alberto and Marcuzzi, Annalisa and Crovella, Sergio}
}
@article {1600,
	title = {Comments on {\textquoteright}{\textquoteright}Geranylgeraniol--a new potential therapeutic approach to bisphosphonate associated osteonecrosis of the jaw" by Ziebart T et al. (2011).},
	journal = {Oral Oncol},
	volume = {47},
	year = {2011},
	month = {2011 May},
	pages = {436-7; author reply 438},
	keywords = {Bone Density Conservation Agents, Diphosphonates, Diterpenes, Humans, Jaw Diseases, Osteonecrosis},
	issn = {1879-0593},
	doi = {10.1016/j.oraloncology.2011.02.017},
	author = {Marcuzzi, Annalisa and Zanin, Valentina and Crovella, Sergio and Pontillo, Alessandra}
}
