TY - JOUR T1 - Acute myelitis as presenting symptom of HIV-HTLV-1 co-infection. JF - J Neurovirol Y1 - 2016 A1 - Cucca, A A1 - Stragapede, L A1 - Antonutti, L A1 - Catalan, M A1 - Caracciolo, I A1 - Valentinotti, Romina A1 - Granato, A A1 - D'Agaro, P A1 - Manganotti, P AB -

A 21-year-old woman presented with acute-onset spastic paraparesis. The MRI spinal scan revealed a contrast-enhanced T2 hyperintensity between C5-T2. The most common neurotropic pathogens were excluded by first level tests. Under suspicion of an acute immune-mediated myelitis, a corticosteroid therapy was administered. However, a seropositivity for both human immunodeficiency virus (HIV) type 1 and human T-lymphotropic virus (HTLV) subsequently emerged. An antiretroviral therapy was started while steroids discontinued. Patient's clinical conditions remained unchanged. HIV-HTLV-1 co-infection should be included in the differential diagnosis of any acute myelitis, even in patients with a preserved immune status and no risk factors.

U1 - http://www.ncbi.nlm.nih.gov/pubmed/27245591?dopt=Abstract ER -