TY - JOUR T1 - Long-term follow-up in children with benign convulsions associated with gastroenteritis. JF - Eur J Paediatr Neurol Y1 - 2014 A1 - Verrotti, Alberto A1 - Moavero, Romina A1 - Vigevano, Federico A1 - Cantonetti, Laura A1 - Guerra, Azzurra A1 - Spezia, Elisabetta A1 - Tricarico, Antonella A1 - Nanni, Giuliana A1 - Agostinelli, Sergio A1 - Chiarelli, Francesco A1 - Parisi, Pasquale A1 - Capovilla, Giuseppe A1 - Beccaria, Francesca A1 - Spalice, Alberto A1 - Coppola, Giangennaro A1 - Franzoni, Emilio A1 - Gentile, Valentina A1 - Casellato, Susanna A1 - Veggiotti, Pierangelo A1 - Malgesini, Sara A1 - Crichiutti, Giovanni A1 - Balestri, Paolo A1 - Grosso, Salvatore A1 - Zamponi, Nelia A1 - Incorpora, Gemma A1 - Savasta, Salvatore A1 - Costa, Paola A1 - Pruna, Dario A1 - Cusmai, Raffaella KW - Adolescent KW - Anticonvulsants KW - Attention Deficit Disorder with Hyperactivity KW - Child KW - Child, Preschool KW - Electroencephalography KW - Epilepsy KW - Female KW - Gastroenteritis KW - Humans KW - Longitudinal Studies KW - Male KW - Neurologic Examination KW - Retrospective Studies AB -

BACKGROUND: The outcome of benign convulsions associated with gastroenteritis (CwG) has generally been reported as being excellent. However, these data need to be confirmed in studies with longer follow-up evaluations.

AIM: To assess the long-term neurological outcome of a large sample of children presenting with CwG.

METHODS: We reviewed clinical features of 81 subjects presenting with CwG (1994-2010) from three different Italian centers with a follow-up period of at least 3 years.

RESULTS: Follow-up period ranged from 39 months to 15 years (mean 9.8 years). Neurological examination and cognitive level at the last evaluation were normal in all the patients. A mild attention deficit was detected in three cases (3.7%). Fourteen children (17.3%) received chronic anti-epileptic therapy. Interictal EEG abnormalities detected at onset in 20 patients (24.7%) reverted to normal. Transient EEG epileptiform abnormalities were detected in other three cases (3.7%), and a transient photosensitivity in one (1.2%). No recurrence of CwG was observed. Three patients (3.7%) presented with a febrile seizure and two (2.5%) with an unprovoked seizure, but none developed epilepsy.

CONCLUSIONS: The long-term evaluation of children with CwG confirms the excellent prognosis of this condition, with normal psychomotor development and low risk of relapse and of subsequent epilepsy.

VL - 18 IS - 5 U1 - http://www.ncbi.nlm.nih.gov/pubmed/24780603?dopt=Abstract ER -