%0 Journal Article %J J Pediatr %D 2015 %T Impact of Surgery for Neonatal Gastrointestinal Diseases on Weight and Fat Mass. %A De Cunto, Angela %A Paviotti, Giulia %A Travan, Laura %A Bua, Jenny %A Cont, Gabriele %A Demarini, Sergio %X

OBJECTIVE: To compare growth, fat mass (FM), and fat-free mass in surgical infants vs matched controls at similar postconceptional age (PCA).

STUDY DESIGN: Anthropometric and body composition measurements by air-displacement plethysmography (PeaPod-Infant Body Composition System; LMI, Concord, California) were performed at the same PCA in 21 infants who received gastrointestinal surgery and in 21 controls matched for gestational age, birth weight, and sex.

RESULTS: Despite similar anthropometry at birth, postsurgical infants were shorter (50.4 [4.7] cm vs 53.2 [4.1] cm, P = .001), lighter (3516 [743] g vs 3946 [874] g, P < .001), and had lower FM content (%FM 14.8 [4.7]% vs 20.2 [5.8]%, P < .0001) than their peers at similar PCA (43 [4] weeks). All surgical infants but 1 (20/21) received parenteral nutrition (PN). Mean PN duration was 40 (30) days. Five infants in the control group received PN because of prematurity for 15 (9-30) days. Nine infants in the surgical group and 1 in the control group had PN-associated cholestasis.

CONCLUSIONS: Neonates having surgery for gastrointestinal diseases were shorter, had lower weight, and lower FM content than their peers, despite receiving more PN. Body composition evaluation and monitoring may help optimize growth in these newborns.

%B J Pediatr %V 167 %P 568-71 %8 2015 Sep %G eng %N 3 %1 http://www.ncbi.nlm.nih.gov/pubmed/26148657?dopt=Abstract %R 10.1016/j.jpeds.2015.06.013