%0 Journal Article %J Pediatr Rheumatol Online J %D 2015 %T Unusual onset of a case of chronic recurrent multifocal osteomyelitis. %A Barrani, M %A Massei, F %A Scaglione, M %A Paolicchi, A %A Vitali, S %A Ciancia, E M %A Crovella, S %A Caparello, M C %A Consolini, R %X

BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition that commonly affects the clavicle and pelvis.

CASE PRESENTATION: We report here a case a 12 years old girl with CRMO arising with recurrent episodes of left supraorbital headache, followed by the appearance of a periorbital dyschromia. Magnetic resonance imaging (MRI) of the skull and orbits revealed an important subacute inflammatory process. Few months after, the child presented a painful swelling of the left clavicle; the histological examination of the related biopsy allowed to establish the diagnosis of CRMO.

CONCLUSION: CRMO presenting as acute headache involving neurocranium is rare; to our knowledge this is the first recognized case in the world literature. This pathological condition is frequently misdiagnosed as infection or neoplasm and needs a deep investigation for the differential diagnosis. The physical, laboratoristic and instrumental diagnostic investigations of the patient and the treatment employed are described in detail.

%B Pediatr Rheumatol Online J %V 13 %P 60 %8 2015 %G eng %N 1 %1 http://www.ncbi.nlm.nih.gov/pubmed/26653878?dopt=Abstract %R 10.1186/s12969-015-0058-0