%0 Journal Article %J Rheumatol Int %D 2013 %T A comparative analysis of serologic parameters and oxidative stress in osteoarthritis and rheumatoid arthritis: reply to Mishra and colleagues. %A Girardelli, M %A Bianco, A M %A Marcuzzi, A %A Crovella, S %K Arthritis, Rheumatoid %K Female %K Humans %K Inflammation Mediators %K Lipids %K Male %K Osteoarthritis %K Oxidative Stress %X

In chronic diseases such as rheumatoid arthritis and osteoarthritis, the progression of the disease is characterized by stress oxidative, inflammation, and elevated levels of cholesterol. In mevalonate kinase deficiency, an auto-inflammatory disease, the correlation between inflammation and cholesterol levels is opposite. The metabolic pathway that underlies the production of cholesterol is the mevalonate pathway; it is also essential for the biosynthesis of isoprenoids involved in the control of several cell functions. This divergence of cholesterol levels, associated with these two inflammatory disorders, is probably due to a different etiology, pathogenesis, and progression.

%B Rheumatol Int %V 33 %P 2445-6 %8 2013 Sep %G eng %N 9 %1 http://www.ncbi.nlm.nih.gov/pubmed/22562750?dopt=Abstract %R 10.1007/s00296-012-2436-y %0 Journal Article %J Aliment Pharmacol Ther %D 2012 %T Letter: inflammatory bowel disease, complementary and alternative medicine, and genetics. %A Bianco, A M %A Vuch, J %A Girardelli, M %A Zanin, V %A Marcuzzi, A %A Crovella, S %K Complementary Therapies %K Female %K Humans %K Inflammatory Bowel Diseases %K Male %K Medication Adherence %B Aliment Pharmacol Ther %V 35 %P 1110-1 %8 2012 May %G eng %N 9 %1 http://www.ncbi.nlm.nih.gov/pubmed/25099779?dopt=Abstract %R 10.1111/j.1365-2036.2012.05065.x