<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Auriti, Cinzia</style></author><author><style face="normal" font="default" size="100%">Fiscarelli, Ersilia</style></author><author><style face="normal" font="default" size="100%">Ronchetti, Maria Paola</style></author><author><style face="normal" font="default" size="100%">Argentieri, Marta</style></author><author><style face="normal" font="default" size="100%">Marrocco, Gabriella</style></author><author><style face="normal" font="default" size="100%">Quondamcarlo, Anna</style></author><author><style face="normal" font="default" size="100%">Seganti, Giulio</style></author><author><style face="normal" font="default" size="100%">Bagnoli, Francesco</style></author><author><style face="normal" font="default" size="100%">Buonocore, Giuseppe</style></author><author><style face="normal" font="default" size="100%">Serra, Giovanni</style></author><author><style face="normal" font="default" size="100%">Bacolla, Gianfranco</style></author><author><style face="normal" font="default" size="100%">Mastropasqua, Savino</style></author><author><style face="normal" font="default" size="100%">Mari, Annibale</style></author><author><style face="normal" font="default" size="100%">Corchia, Carlo</style></author><author><style face="normal" font="default" size="100%">Prencipe, Giusi</style></author><author><style face="normal" font="default" size="100%">Piersigilli, Fiammetta</style></author><author><style face="normal" font="default" size="100%">Ravà, Lucilla</style></author><author><style face="normal" font="default" size="100%">Di Ciommo, Vincenzo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Procalcitonin in detecting neonatal nosocomial sepsis.</style></title><secondary-title><style face="normal" font="default" size="100%">Arch Dis Child Fetal Neonatal Ed</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Arch. Dis. Child. Fetal Neonatal Ed.</style></alt-title></titles><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2011 Mar 15</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">ENG</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;OBJECTIVE: To investigate the accuracy of procalcitonin (PCT) as a diagnostic marker of nosocomial sepsis (NS) and define the most accurate cut-off to distinguish infected from uninfected neonates. SETTING: Six neonatal intensive care units (NICUs). PATIENTS: 762 neonates admitted to six NICUs during a 28-month observational study for whom at least one serum sample was taken on admission. MAIN OUTCOME MEASURES: Positive and negative predictive values at different PCT cut-off levels. RESULTS: The overall probability of an NS was doubled or more if PCT was &gt;0.5 ng/ml. In very-low-birth-weight (VLBW) infants, a cut-off of &gt;2.4 ng/ml gave a positive predictive value of NS near to 50% with a probability of a false-positive diagnosis of NS in about 10% of the patients. CONCLUSIONS: In VLBW neonates, a serum PCT value &gt;2.4 ng/ml prompts early empirical antibiotic therapy, while in normal-birth-weight infants, a PCT value ≤2.4 ng/ml carries a low risk of missing an NS.&lt;/p&gt;</style></abstract><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/21406453?dopt=Abstract</style></custom1></record></records></xml>