<style face="normal" font="default" size="100%">Severe inflammatory bowel disease associated with congenital alteration of transforming growth factor beta signaling.</style>

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<style face="normal" font="default" size="100%">Severe inflammatory bowel disease associated with congenital alteration of transforming growth factor beta signaling.</style>

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<style face="normal" font="default" size="100%">Forkhead box protein 3 (FOXP3) mutations lead to increased TH17 cell numbers and regulatory T-cell instability.</style>

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<style face="normal" font="default" size="100%">Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome.</style>