R21 EY027880 / EY / NEI NIH HHS / United States R01 EY024233 / EY / NEI NIH HHS / United States MC_UU_12015/1 / / Medical Research Council / United Kingdom R01 EY020483 / EY / NEI NIH HHS / United States R01 EY014685 / EY / NEI NIH HHS / United States